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Question about Genetics: Introduction

Biology

Originais Teachy

Genetics: Introduction

Very Hard

(Originais Teachy 2023) - Question Very Hard of Biology

Hemophilia A is a genetic disease linked to the X chromosome and is characterized by a deficiency or absence of clotting factor VIII in the blood. Imagine a couple planning to have children where the man is hemophilic. The task is to discuss the probability that their female descendants will be hemophilic or carriers of hemophilia. Consider the man's genotype as XhY and the woman's as XX, and that hemophilia is conditioned by a single recessive gene. Explain the process of X-linked inheritance and how it affects the phenotypic expression of the disease in male and female individuals. Additionally, address the concept of genetic recombination in meiosis processes and its influence on determining the genotype of gametes, considering the possibility of crossing over during the formation of the hemophilic man's spermatozoa.

Answer sheet:

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